A cohort study of sex differences and prognostic biomarkers in colerctal cancer

Accumulating evidence indicates that CRC is a heterogeneous disease, which affects outcome beyond what can be predicted by disease stage and other conventional prognostic factors. Thus, there is a great need to identify new biomarkers to enable a more accurate prognostication, and to help select patients for adjuvant treatment. In this thesis, the associations of a series of putative biomarkers with survival, treatment response and clinicopathological factors were investigated in a large cohort